Abstract:
A cross-sectional study conducted during the period from February to
July 2012, compared serum activates of Aspartate transaminases,
Alanine transaminases and Alkaline phosphatase of 60 Sudanese
patients with type 2 diabetes mellitus ( as a test group) and 40
apparently healthy volunteers (as a control group). Participants in this
study were from Military Hospital in Omdrman. Age and gender of
test group were matched with the control group. The serum activities
of AST, ALT and ALP were measured by using auto analyzer from
Cobas Integra 400 plus / Mindary -380.
serum AST and ALT showed insignificant difference, whereas serum
ALP was significantly raised in the test group compared to control
group .
For the test group ,both serum AST and ALT showed no correlation
with the duration of disease, while plasma ALP showed a positive
correlation with the duration of diabetes mellitus.
From this study, it is concluded that: in Sudanese patients with type 2
diabetes mellitus the plasma ALP is raised, serum AST and ALT are
not affected. In addition, serum AST and ALT showed no correlated
with the duration of diabetes mellitus, whereas serum ALP is
positively correlated with the duration of diabetes mellitus.
Both serum AST and ALT showed no correlation with the duration of
disease, while serum ALP showed a positive correlation with the body
mass index of diabetes mellitus.
