Assessment of levels plasma total calcium and magnesium in pregnant women with preeclampsia in Khartoum state

Abstract

This was cress section study conducted in, Khartoum state, in El Saudi Hospital during the period of March to June 2012, to assess plasma total calcium and magnesium in Sudanese pregnant women with preeclampsia . Blood sample was taken from 50 patients were clinically diagnosed preeclampsia as a test group and 30 pregnant women as control group. Plasma calcium and magnesium were measured by Colorimetric method and data were analysed by using SPSS . Plasma total calcium was significantly lower in patients (8.25 ± 0.20 mg/dL) compared with controls (9.00 ± 1.19 mg/dL), (P = 0.00), and magnesium levels were significantly lower in patients (1.67 ± 0.12 mg/dL) than controls, (2.03 ± 0.16 mg/dL),( P = 0.00). Also result obtained showed that, Systolic and diastolic blood pressure was significantly increased in preeclamptic women (147.20± 4.39, 96.06± 3.383 mmHg) compared to health pregnant (108.37 ±5.93, 77.13 ±5.923, mmHg)( p < 0.05 ( respectively. Also plasma total calcium and magnesium showed significant strong negative correlation with mean arterial blood pressure in preeclamptic women (r = - 0.751 P = 0.00), (r = -0.797 P = 0.00) respectively. In conclusion, there was decreased in the level of total serum calcium and magnesium in preeclampsia, also there is significant strong negative correlation between means arterial blood pressure and both serum total calcium and magnesium.