Abstract:
Across sectional study was conducted during April 2012 to
june 2012 on70 leukemic patients 43 males and 27
females
, who were attended Radiation and Isotope
centre of Treatment , Khartoum , other 16 non leukemic
individuals were randomly selected to serve as control
group.Blood sample werecollected from patients and
control groups for determination of plasma creatinine,
uric acid and total cholesterol .The analysis of samples by
using commercial kits and instruments of Biosystem.
Acute myeloid leukemia and Acute lymphocytic leukemia
were found in young patients , while chronic myeloid
leukemia and chronic lymphocytic leukemia were in the
middle and older ages. Uric acid is significantly elevated
in leukemic patients( p=o.ooo) and patients with AML and
CML show high uric acid . In comparison means of uric
acid level in leukemic patients with the control group,
there was different. The creatinine is mildly elevated in
leukemic patients.(p=o.ooo) , AML and CML patients show
high creatinine.
in comparison means of creatinine level in leukemic
patients with control groups there was different.
Total cholesterol is significantly low in leukemic patients
(p=o.ooo).
ALL and CML patients show more lower in total cholesterol
levels . In comparison means of total Cholesterol level in
leukemic patients with the control groups , there was
significant different.
we concluded from this study that , the uric acid is
high ,creatinine is mild elevated, while total cholesterol is
low in leukemic patients compared to non leukemic.
