Abstract:
This is a cross- sectional study conducted during the period from
March 2012 to October 2012. The aim of this study to assess the
serum levels of creatinine and urate among Sudanese with type2
diabetes mellitus. Sixty patients with type2 diabetes mellitus were
selected as a test group from the military hospital in Khartoum
state, Sudan.
The test group was compared with a control group which included
40 healthy volunteers. Age and gender of the test group were
matched with
the control group. Blood specimens were collected
from both groups and the serum levels of creatinine and urate were
estimated . Cobas integra 400plus from Roche campany was used for
measurement of serum levels of creatinine and urate . Statistical
package for social science (SPSS version 11.5) computer software was
used for data analysis.
The results of this study indicates a significant increase in the
means of the serum levels of creatinine and urate in type 2 diabetic
patients (test group) compared with non diabetic subjects as control ( P ≤ 0.05 ).
The results of the current study indicates a significant, strong positive
correlation between the duration of the diabetes mellitus type 2 with both serum
levels of creatinine and urate. Also significant a weak positive relationship was
observed between the serum levels of creatinine and the BMI and Insignificant a weak
positive relationship was observed between the serum levels of urate and the BMI.
Inconclusion; the serum levels of creatinine and urate are increased
in diabetic patients with type 2 diabetes mellitus.There is strong
positive correlation between creatinine and urate and the duration of
diabetes mellitus. There is a weak relationship between the serum
levels of creatinine and the BMI , and no correlation between the
serum levels of urate and the BMI .
