Synthesis of some derivatives of 1,4-Naphthoquinone

Abstract

In this work, 2–{5–[(2–phenylhydrazinylidene)methyl] furan–2–yl}naphthalene-1,4-dione and 2–{4-[(2– phenylhydrazinyliden)methyl]phenyl}naphthalene-1,4-dione have been synthesized by reaction of 1-(furan-2-ylmethlidene)- 2-phenylhydrazine and 1-benzylidene-2-phenylhydrazine as hydrazones with 1,4-naphthoquinone according to a well documented procedure. Access to furylnaphthoquinones from un activated quinones requires acid-inuced conditions, however oxidation coupling reaction of activated quinones proceed under neutral condition. The hydrazones were prepared from the commercially aldehydes and phenyl hydrazine.