Abstract:
A local strain of Pseudomonas aeruginosa was isolated from a
patient suffering from burns. The isolated strain was characterized by
morphological and biochemical examinations.
This bacterial strain showed high copper uptake when inoculated
and incubated with different copper sources such as cupric chloride
dihydrate, cupric nitrate 3 hydrate and cupric sulfate, respectively.
A comparison with two other species of bacteria indicated that the
copper uptake by Pseudomonas aeruginosa was significantly higher than
that of Bacillus thurengenesis or Enterobacter aerogenes (P<0.05). The
minimum concentration of copper compound that gave 50% copper
uptake was shown to be the lowest in Pseudomonas aeruginosa,
irrespective of the copper compound being used as a copper source.
An attempt was made to investigate the possible effect of certain
medicinal plants and commercial antibiotics on the growth of
Pseudomonas aeruginosa. Out of 18 different medicinal plants examined,
only Thymus capitatus (30 mg) gave a zone of inhibition 10mm. These
medicinal plants were shown to be more effective against Bacillus
thurengenesis and Enterobacter aerogenes in comparison to
Pseudomonas aeruginosa.
The hematological findings indicated that patients infected with
Pseudomonas aeruginosa have significant differences in comparison to
the control gave in the several parameters examined serum copper
(P<0.05), serum iron (P<0.05), Iron binding capacity (P<0.05), serum
ceruloplasmin (P<0.05) and serum transferring (P<0.05). Two types of
control groups were used, healthy individuals and uninfected patients
who had burn injury.
