Abstract:
This is s case control study carried out in Khartoum state in Maternity Hospitals during
the period from June2012 to September 2012 .Fifty hypertensive women with
preeclampsia were selected 25 during pregnancy and 25 after 24 hours post delivery, in
addition to 20 healthy pregnant women were selected as control group. The study group
selected with age range 18and 45. Four and half ml of venous blood was withdrawn from
each participant, placed in a test tube containing tri sodium citrates which act as
anticoagulant.
Prothrombin time (PT), activated partial thromboplastin time (APTT) and fibrinogen
level were measured using an automated coagulometer adjusted at 37C⁰. The results
showed increased number of subjects aged group between (25 and 35) years, 30
particepants.Insignificant increase in PT in pregnant women with preclampsia compared
to control group (P value <0.05) and insignificant increase in postpartum group compared
to control group. APTT showed significant increase in preeclampatic pregnant group
compared to control group. Postpartum group also showed significant increase when
compared to control group (P value < 0.05). Fibrinogen level showed significant increase
in both groups compared to control group (P value <0.05). There was insignificant
increase in PT,APTT and fibrinogen level according to age group .PT and APTT increase
insignificantly in pregnant women with preeclampsia compared to post partum group but
fibrinogen decrease insignificantly (p value>0,05).
This results showed that PT in preeclapmatic women was increase insignificantly while
APTT and fibrinogen level are increased significantly so the determination of these
parameters are recommended to prevent bleeding complications
