Abstract:
There is a strong relationship between cigarette smoking and haemostatic
parameters to increase the risk of cardiovascular events. This is case control
study carried out in Khartoum state from May 2012 to July 2012, aim to measure
the prothrombin time, partial thromboplastin time and fibrinogen level among
the Sudanese smoker,100 blood sample were collected randomly from cigaree
smoker people with an age ranged between (21-60 years)and duraon of
smoking ranged between (1- 40 years). The data was classified in to four groups
according to age of the smoker and three different groups according to duration
of smoking. Fifteen blood samples collected from apparent healthy non smoker
individual as control group. 2.5ml of venous blood was drowning from each
individual; the results were analyzed by use SPSS version 11.5 and express as
mean. Prothrombin Time was significantly lower in cigarette smokers group
(mean 11.8 sec) compared with nonsmokers group (mean 13.8sec). The
Prothrombin also negatively correlating with the duration of smoking and it's
statistically significant, however, the partial thrombplastin Time was not changed
significantly in the smokers groups, but correlating with age, and the duration of
smoking and it's statistically significant.
Fibrinogen was significantly increased for the cigaree smokers group (4.09g/dl)
compared to non-smokers (2g/dl), and correlang with age and with the duraon
of smoking.
