Abstract:
This is a prospective, descriptive and cross-sectional study
aimed to detect autoimmune hemolytic anemia among
chronic
lymphocytic
leukemia
Sudanese
patients
attending Radiation and Isotopes center in Khartoum
state during the period from January to June 2011.
A total of fifty Sudanese leukemic patients were enrolled
in this study, 32 (64%) males and 18 (32%) females,
their age ranged from 46 to 85 years, and 28% were
receiving treatment while 72% were untreated.
2.5 ml EDTA anticoagulated blood sample was collected
from
each
antiglobulin
patient
test
and investigated
using direct
(Coomb’s
test),
complete blood
count, reticulocyte count, and Lieshman’s stained
blood film.
The mean haemoglobin concentration and reticulocyte
count was 9.7 g/dl and 3.1 % respectively. Direct
antiglobulin test was positive in 6 (12%) cases and
negative in 44 (88%), this frequency of positive DAT is
similar to the known frequency in western countries.
Blood film showed different degrees of spherocytosis and
reticulocytosis.
The results of this study showed that no relation between
treatment
of
chronic
lymphocytic
leukemia
and
autoimmune hemolytic anemia
