Abstract:
The value of transaminases, total protein and albumin as indicator of severity of
pre-eclampsia among Sudanese patients was studied in the period 1st May to end
of October 2oo6. It was crosssectional test and control study.
The Study was carried out as a multi center study in Khartoum state in
different maternity units, including, Khartoum Teatching Hospital and
Omdruman maternity Hospital.
Information were collected from the patients by taking history through a
questionnaire .laboratory examination and analysis of plasma transaminases,
total protein and albumin were done. Urine was test for protein.
A total of 50 patients admitted with pre-eclampsia were compared with
30 ladies with normal pregnancy, both were selected at third trimester of
pregnancy.
Most of the patients were primgravida in the age group between 18 to 39
years. The control groups match the test group. The result obtained for both
groups were statistically analyzed using T test correlation.
The average value of plasma ALT among
the control group
was.11.03u /L compared to 47.74u/l in those patients admitted as cases of pre-
eclampsia and the average value of plasma AST among the control group
was10.166U /L compared to 42.66u/L in those patient admitted as cases of pre
eclampsia. The average value of plasma Total protein among the control group
was 72.56g /L compared to 52.04g/L in those patient admitted as cases of pre
eclampsia , the average value of plasma albumin among the control group
was43.26g /L compared to 30.2g/L in those patients admitted as cases of pre-
eclampsia . The results obtained showed that there were significance difference
between plasma transaminases,total protein and albumin in control groups and
test groups (p<0.05). In conclusion , the study confirms that the value of plasma
transaminase, total protein and albumin have good correlation with severity of
pre-eclampsia.
