Abstract:
This is a cross sectional study, conducted in Abu Aagla center in Wad Medani
from 9 /April /2012 to 2 /May /2012, to measure PT, APTT and platelets count
of type 1 diabetic patients study population, 4.5ml venous blood collected from
fifty of type 1 diabetic patients in trisodium citrate anticoagulant to measure
PT and APTT and 2.5ml in EDTA to measure platelet count The research
reveal the flowing results:
There was insignificance different in PT in the patients group compared to
control group (P value=0.73), insignificant increase according to the duration
of disease (P value=0.15), there was insignificant difference in PT/second
according to insulin dose received per day, (P value =0.18), there was
insignificant difference in PT/second of diabetic patients with hypertension
compared with to control (P value=0.09) and there was insignificant increased
in PT/second according to onset of disease compared to control group (P value
=0.18).
There was a significant increase in APTT/second of patients mean (57.9±SD)
compared to control group mean {29.5±SD)/second, (P value=0.00).
Insignificant difference was associated with duration of the disease (P
value=0.54). Insignificant difference in APTT/second according to insulin dose
received per day (P value=0.96). Insignificant difference of APTT/second in
diabetic patients with hypertension compared to control group (P value=0.72).
There was significant increase in APTT/second according to onset of the
disease
mean
(57.9±SD)/second,
compared
to
control
group
mean
(29.0±SD) /second, (P value=0.00).
There was significant increase in platelets count×10 9 /dL in the patients mean
(216±SD) ×109/L compared to control group mean (166±SD) ×10 9/L, (P
value=0.00). Insignificant difference in duration of disease (P value =0.41).
Insignificant decrease of parameters according to insulin dose received per
day (P value=0.28). Significant decrease in diabetic patients with
hypertension mean (197.3±SD) ×109/L, compared to control group means
(227.4±SD) ×109/L (P value= 0.03). Increase significantly according to onset
of the disease mean (216.5±SD) ×109/L, compared to control group means
(166.4±SD) ×109/L, (P value=0.00).
