Abstract:
This analytical case control study conducted in Jabber Abu AI-iz
Diabetic health center and Saad Rashwan Medical center during the
period from June to February 2014, aimed to evaluate serum levels of
zinc and magnesium among Sudanese patients with type II Diabetes
mellitus. Sixty three samples were taken and compare with fourty five
apparently healthy volunteer as a control group. Participants age ranged
between 35-70 years old. Zn was assessed using standard biochemical
technique , glucose and Mg were examined using spectrophotometric
technique. Data was analyzed by SPSS version 15.
The mean serum level of zinc (mg/L) in test and control group (0.457 ±
0.11) (0.496 ± 0.07) (P- value= 0.047), Mg (1.943 ± 0.28) (2.291 ± 0.27)
(P value= 0.000) and glucose (181 ± 84.4) (86 ± 12.7) (P value= 0.000)
respectively.
The level of Mg, Zn and glucose were significantly difference in test
group as compared to control group (P value ˂0.05).
In diabetic group there was no correlation between zinc ,Magnesium and
glucose with duration of disease (p > 0.05). There was weak negative
correlation between glucose and Zinc (r = -0.229 ,P-value =0.017) and
also glucose with Mg ( r = -0.309 ,p value =0.001).
Age showed no correlation with zinc and glucose (P<0.001),but weak
negative correlation with magnesium (r= -0.145 ,p-value =0.134).
This study conclued that ,the levels of zinc and magnetism are
differentially changed in the studied groups ,they decrease in diabetic
patients with type II diabetes mellitus
