Abstract:
A total of 90 patients with gastrointestinal symptoms, and who
attending Khartoum Teaching Hospital during the period from April to
October 2012, were enrolled in this study. Out of them 35 (38.9%) were
males and 55 (61.1%) were females, their age ranges from 15-60 years
with mean (33.2).The aim of this study was to detect frequency of
Helicobacter pylori IgM, IgG antibodies, and to determine the
relationship between the presence of antibodies and certain factors
such as (sex, age and genetic susceptibility).
90 serum specimens were collected from patients, and analysed
by ELISA technique.
The results showed that 19 (21.1%), 57 (63.3%) were positive for
IgM antibody and IgG respectively, while 15 (16.7%) were positive for
both.
Females were more affected than males, high frequency of
positive results was observed among 15-30 age groups. Statistical
analysis showed that there was insignificant correlation between age,
gender, genetic susceptibility and presence of Helicobacter pylori
antibodies (P >0.05).
