Abstract:
This is across sectional analytical study conducted at Um Rawaba
teaching Hospital and Alobaid teaching Hospital. The study performed in 120
patients EDTA blood samples were collected to perform the hemoglobin
electrophoresis, estimate of Hemoglobin (Hb), Packed Cell Volume (PCV), Red
Blood Cells (RBCs) count, Mean Cell Volume (MCV), Mean Cell Hemoglobin
(MCH), Mean Cell Hemoglobin Concentration (MCHC), Total White Blood
Cells (TWBCs) count, platelets count, Reticulocyte, and Differential count.
Samples were collected from known patient SS=70, AS=16, SF=4 and AA=30
as control, from male and female. Distributed per tribes and ages was reported.
The study showed there was significant decrease Hb6.6g/dl, PCV20.5% and
RBCs2.3x1012/L p-value 0.00 in HbSS and Hb AS there was no differences
between sickle cell disease and sickle cell trait of full blood count due to area of
meal nutrient, there was difference between healthy and sickle cell disease
significant decrease Hb, PCV and RBCs p-value0.00 in HbSS and significant
increase Hb, PCV and RBCs p-value0.00 in HbAA, Significant increase
TWBCs and plt p-value 0.00 in Hb SS.
In sickle cell disease (Hb), (RBCs) and (PCV) was low compare with
control but (Mcv), and (WBCs) was high, some time is high due to infection.
The reticulocyte and nucleated red blood cells (NRBCs) are present in high
number than normal level p-value 0.00.
