Abstract:
The main aim of this study is to investigate infection of pregnant women by
rubella and Cytomegalovirus ( CMV ) in Khartoum State, during the period
from March to July , 2013 .
Blood samples were aseptically, collected from ninety pregnant women
(n=90) with all three trimesters of pregnancy attending different antinatel
clinics (Omdurman Teaching Hospital , Khartoum North Teaching Hospital
, and Alsaudi Hospital).
Enzyme- Linked Immunosorbent Assay (ELISA) was used to detect
rubella and CMV ( IgM and IgG ) antibodies in the sera of all tested
women .
The results obtained that IgM for rubella and CMV were 13.3% and
22.2% , respectively , while IgG for rubella and CMV were 74.4% and
77.8% , respectively .
The highest frequency of rubella IgM ( 27% ) was detected among the age
group 26-31 years , the lowest ( 5% ) was observed among the age group 38-43
years ; while the highest rubella IgG ( 80 % ) was detected among the age
group 38-43 years , the lowest ( 67% ) was observed among the age group 20-
25 years.
Moreover , while the highest frequency of CMV IgM ( 28 % ) was detected
among the age group 20 - 25 years , the lowest ( 14 % ) was observed among
the age group 26 - 31 years . For CMV IgG while the highest frequency (
86 % ) was detected among the age group 26-31 years , the lowest ( 72% )
was observed among the age group 20-25 years .
The highest frequencies of positive rubella and CMV IgM and IgG were
observed among the first trimester of pregnancy .
However , no significant difference (P > 0.05) was observed among the
three trimesters and the different age groups of all pregnant women
examined in this study .
