Abstract:
Human papilloma virus (HPV) infection is the main cause of cervical
cancer. HPV and cervical abnormalities further investigation in Sudan,
one of the main objectives of this study is to demonstrate association
between HPV infection and cytological changes .To screen study group
for presence of cytological a typia using Papanicolaou stain. This cross
sectional descriptive study was performed at Sudan University of
Sciences and Technology. Cytology samples were collected from
obstetrics and gynecology clinic in , Khartoum Teaching Hospital
and Omdurman Friendship Hospital. During the period between
February and May 2011. A total number of two hundred cervical
smears were collected from woman in deferent age suffering from
gynecological symptoms. Samples were smeared on microscopical
slides and stained with Papanicolaou stain and screened primary
with the investigator and results were confirmed by supervisor.
The cytological findings of smears were 145 (72.5%) normal,
50(25%) with different type of infection ( Candida infection 14(7%)
,Trichomonas vaginals 14(7%), HPV infection 16(8%), Candid ,HPV &
Actinomyces infection 1(.5%) Tricomonas & HPV infection 1(.5%),
Candida infection & HPV infection 2(1%), Adenocarcinoma & HPV
infection 1(.5%) , Leptothrix & Trichomonas vaginals 1(.5%) ) , 3(1.5%)
suffering from Adenocarcinoma and 2(1%) cervical glandular
intraepithelial neoplasia (CGIN), This study recommends that
cytological investigation from women suffering from gynecological
symptoms HPV infection should be taken in consideration during
gynecological examination, As it is one of the main causes of cervical
cancer. Our findings confirm low levels of cervical cancer screening, and
considered amount of (HPV) infection are present among women in
Khartoum state.
