Abstract:
This
study
conducted
during
the
period
September 2010, compared serum levels of
March
to
Alanine
transaminase, To study the effect of diabetes mellitus on
the serum activity of ALT, of 60 diabetic patients, chosen
from diabetic center, Khartoum North. And hag Elssafi
hospital, ( in Khartoum state) and 20 apparently, health
individuals as controls.
Patients with diabetes mellitus had significantly higher
serum ALT levels, as measured by
spectrophotometric
method. The main serum ALT was 25.7(SD 7.9)u/l, in the
diabetic group, compared to 17.9 (SD5.7)u/l in the control
group (p<0.05).but the increased ALT were within the
normal reference value.
To study the effect of the duration of diabetes mellitus on
serum levels of the liver enzyme. Alanine transaminase
(ALT), the diabetic group of patient (n=60) was divided
into two subgroups; <10 years duration of the disease
(n=27) and > 10 years duration (n=33). It was found that,
serum ALT, they show significant increase with increase
duration of the disease. But still any alteration of activity
were within the normal value
The following result was obtained. The mean serum ALT
levels (<10 years: 22.5±8.1u/l and > 10 years:28.3±6.8
u/l p<0.05).
To study the effect of age with diabetes mellitus on serum
levels of Alanine transaminase (ALT), the diabetic group of
patient (n=60) was divided into two subgroups; <40 years
(n=9) and > 40 years duration (n=51). It was found that,
serum ALT, although they were significantly raised in the
diabetes group (n=60), they don't show any significant
increase with increase of age.
The following result was obtained. The mean serum ALT
levels (<40 years: 24.9±9.4 u/l and > 40 years:25.8.0±7.7
u/l p>0..05)
To study the effect of sex with diabetes mellitus on serum
levels of Alanine transaminase (ALT), the diabetic group of
patient (n=60) was divided into two subgroups; male
(n=39) and female (n=21). It was found that, serum ALT,
although they were significantly raised in the diabetes
group (n=60), they don't show any significant increase
with sex.
The following result was obtained. The mean serum ALT
levels
(male:
p>0.05)
