Abstract:
This is a cross sectional analytical study conducted
in Omdurman maternity hospital during period
march 2012 to June 2012; the study was included
50 pregnant women with pre-eclampsia were
selected randomly with age ranged between (18-
37) years.
25 healthy pregnant women of the same age range
enrolled as control group. Every female interviewed
through especial questionnaire to collect historical
data, citrate blood sample was collected from each
pre-eclampsic pregnant woman, and citrated poor
plasma was immediately harvested and analyzed,
using automated coagulometer for prothrombin
time ( PT ), activated partial thromboplastin time
( APTT), and fibrinogen level.
The mean of PT values of the study group was (13 sec)
and the controls was (13 sec), the mean of APTT value
study group was (51 sec) and the controls was (30 sec),
the mean of fibrinogen level of the study group was
(476mg/dl) and the controls was (296mg/dl).
The study results revealed that there was
insignificant value for prothrombin time of pre-
eclampsic women (P value >0.05) whoever high
with significant increased in activated partial
thromboplastin time and fibrinogen level of pre-
eclamsic women
compared to normal control
mean level (p.value < 0.000).