A Retrospective Study of Amyloid Deposition Among Lymphoma Patients in Khartoum State

Abstract

This is a retrospective study conducted in Khartoum State, during the period from May to August 2005. The objective of this study is to investigate patients who developed amyloid deposition associated with lymphoma of different types. Fifty specimens (biopsies) were collected from patients with different lymphoma types. The results showed deposition of Amyloid in 22 (44%) of the different lymphoma types. Among these, 8 (16%) were Hodgkin's Lymphomas, 2(4%) were Non Hodgkin's Lymphomas, 2(4%) were Burkett's Lymphoma, 1(2%) was large Cell Lymphoma and the remaining 9(18%) were other different types of Lymphomas. Amyloidogenic materials were found to be associated with the most forms of lymphomas. Certain types of lymphomas (Hodgkin's and Burkett's) revealed more concentrations of amyloidogenic materials than others. Thus investigation of lymphoma patients for amyloid deposition are highly recommended. Further advanced studies are to be implemented to disclose the relation between the amyloid and lymphoma according to the causes.