The Prevalence Of Hyperuricaemia (Gout) In Diabetic Patients

Abstract

A prospective study was conducted during the period, April 2004 to April 2005. Hyperuricaemia and diabetes mellitus (D.M) are interrelated diseases and frequently concomitant. In this study a total of (200) subjects were examined for serum uric acid level. Hundred (100) subjects were known diabetics. Twenty-one of them were type I (IDDM) and seventy-nine were type II (NIDDM). Hundred non-diabetic patients were chosen as control group. The diabetic group (n= 100) (Male= 50, Female= 50), were divided into sub groups according to sex, age, duration of diabetes, modes of treatment diet and glycaemic control. A sample from each subject was analyzed for serum uric acid and random blood glucose. The results were statistically analyzed. All patients are suffering from hyperglycaemia. There were significant differences between two means of diabetic patients and control subjects 320mg/dl ± 16.2 mg/dl, 110mg/dl ± 13.0 mg/dl and probability P. < 0.05 respectively. The results obtained showed that there was a highly significant difference in the mean of serum uric acid (mg/dl) for the diabetic patients (7.293 mg/dl ± 0.6332 mg/dl) and the mean of serum uric acid (mg/dl) for the control group (4.902 mg/dl ± 0.1109 mg/dl) P. value < 0.05. Forty five percent (45%) in both types of diabetes were suffering hyperuricaemia while (55%) in both types were not hyperuricaemic. No significant differences were found among gender. Types of diet, poor glycaemic control and old age are found to be risk factors for hyperuricaemia particularly in type II DM. In this study 10 percent from all diabetic patients were found to be typical gouty patients most of them from type II DM. Finally this study showed that the hyperuricaemia and gout are uncommon before the age of 30 years.