Abstract:
Given that the use of Moringa tree in Sudan is restricted on
water treatment from visible impurities, though river water might
be considered as a potential risk of infection.
Therefore, in this study, the aim was to detect and evaluate
the antibacterial and antifungal activities that the Moringa tree
parts, especially the seed kernels, might have.
The suitable clinical samples were collected, pathogens
isolated, identified and purified for subsequent testing.
Based on global reports that suggest the existence of
antimicrobial activity against a spectrum of microorganisms, a
series of in vitro sensitivity tests were carried on 60 clinical
isolates and 6 control strains (bacteria and fungi).
Results proved the hypothesis. An obvious antibacterial
activity was found particularly in seed kernels. Among the control
and clinical isolates; Gram positive bacteria were inhibited
greater than Gram negative bacteria. Staphylococcus aureus
showed the widest zones of inhibition comparatively with
Norfloxacin antibiotic disc. On the other hand, antifungal activity
was relatively weak in comparison with Nystatin and Clotrimazole
antimycotic discs. Inhibition zones were created almost only by
methanol and aqueous extracts of seeds. Candida albicans
showed the widest zones of inhibition among the fungi tested.
In short, results obtained were successful and the extracts
.proved an observable antimicrobial activity
