Abstract:
In spite of various side effects and serious complications associated
with the use of combined oral contraceptive pills, it regarded as a safe
and highly effective method of contraception.
In recent years, the usage of combined oral contraceptive pills with low
oestrogen content or without oestrogen are being recommended to
minimize the side effects.
This analytical case control study was conducted in Khartoum state
during the period from June to August 2013. This work aimed to
measure some coagulation parameters PT, APTT and fibrinogen level in
women using of oral contraceptive pills and implanon. Fifty women
were selected as volunteers and considered as case group and other
20 women who didn't use the contraceptive pills or not used implanon
were selected as control group.
Two ml of venous blood was collected in 0.5ml of 3.8% trisodium
citrate containers and investigated for PT, APPT and fibrinogen level by
used of coagulameter (clot), the result were analyzed by SPSS. The
result revealed that the mean of PT 12.6 seconds, APTT 29.9 seconds
and fibrinogen level 261 mg/dL in women using contraceptive pills and
the mean of PT 12.9 seconds , APTT 29.9 seconds and fibrinogen level
241 mg/dL in women using implanon.
In conclusion the result showed significant decrease of fibrinogen level
in women using implanon when compared with control group (P value
<0.05). and no significant differences were noticed in PT, APTT and
fibrinogen in women used contraceptive pills.
