Estimation of Total Serum Calcium and Phosphorous in Sudanese Patients with Thyroid Disorders - A Study in Khartoum State

Abstract

This study was done to determine total serum calcium and serum phosphorus in Sudanese patients with thyroid disorders, the mean of ages of the patients (41.9±13.3) years, in Khartoum state at March to July 2012. This study showed that thyroid disorder is more frequent in female. The levels of total serum calcium and serum phosphorus were measured by using COBAS INTEGRA400and the kits from ROCHE Company. Also the result of this study showed that the mean of the serum total calcium of the test group (of all thyroid disorder whether hyperthyroidism, hypothyroidism or goiter) were significantly increased when compared to control group (p = 0.031), and the mean of the serum phosphorus of the test group were insignificant increased when compared to control group (p= 0.098). Also the study showed there was significantly increase in the mean of the total serum calcium in hyperthyroidism in test group when compared with control group (p=0.002), and the mean of the total serum calcium in hypothyroidism (p=0.999) and goiter (p=0.061) in test group were insignificant increase when compared with control group. Also the study showedthere was significant increase in the mean of the serum phosphorus in hyperthyroidism (p = 0.000), and significant decreased in serum phosphorus in hypothyroidism (p = 0.029) in test group when compare with control group, and the mean of the serum phosphorus in goiter in test group were insignificant change (p = 0.24) when compare with control group. Also the study showed there was significant decrease in the mean of serum total calcium (p=0.004) and serum phosphorus (p=0.000) in hypothyroidism in test group when compared with hyperthyroidism patients. Also the study showed there was significant increase in the mean of serum phosphorus (p=0.005) in hypothyroidism patient in test group when compared with goiter patient. Also the study showed there was significant increase in the mean of serum phosphorus (p=0.027) in hyperthyroidism in test group when compared with goiter patients. Also the study showed there was insignificant change in the mean of serum total calcium in hypothyroidism (p=0.057) and hyperthyroidism (p=0.478) in test group when compared with goiter patient.