The effects of malaria infection on some haematological parameters in School pupils in Port Sudan city

Abstract

The study covers about one hundred and fifty persons between 6- 18 years old in Port Sudan city from May to August, this study aimed to determine the effects of malaria infection on haemoglobin and white blood cells deferential count. Blood samples were collected from school pupils to estimate haemoglobin level, white blood cells differential count and the presence of malaria parasites. Three groups were compared, infected group, pre-infected group and non-infected group. The investigation was done by using Giemsa staining method for malaria and differential counts and Sahli haemoglobinometer to estimate haemoglobin level. The study was showed that the mean haemoglobin levels in infected , pre-infected and non-infected groups were 78.3%, 86.1%, 89% respectively. The differential counts of white blood cells such as neutrophils were found to be 50%, 56.2%, 58% in infected group, pre-infected group and non-infected group respectively. Whereas eosinophils were found to be 3%, 1.7%, 1.2% in infected group, pre-infected group and non-infected group respectively. The basophils were found to be 0.64%, 1.2%, 0.9% in infected group, pre-infected group and non-infected group respectively. The lymphocytes were found to be 44%, 38.7%, 37% in infected group, pre- infected group and non-infected group respectively. finally monocyts were found to be 3.7%, 2.4%, 3% in infected group, pre-infected group and non- infected group respectively. The results showed that the haemoglobin levels decreased in infected group with highly significant differences (P< 0.01)in contrast the monocytes, lymphocytes and eosinophils were increased in infected group with significant differences (P< 0.05, P< 0.05, P< 0.05). The collected immature water stages of mosquitoes from different sites in different units, were identified as culexs’ pupae and larvae.