Abstract:
This study was carried out in Khartoum State during
the period from October 2003 to December 2005. The
study was designed to evaluate the activity of cephalexin
by using National Committee for Clinical Laboratories
Standard (Nccls) modified Kirby-Bauer Disc diffusion
technique against urinary isolates. The total numbers of
urinary isolates were 140 species. The species were
identified as E. coli 93 (66.4%), Klebsiella spp 20(14.3%),
Proteus spp. 12(8.6%), Pseudomonas spp. 10(7.1%),
Staph. aureus 3(2.1%) and Strepto. faecalis 2 (1.4%).
The results obtained from this study showed that
urinary pathogens had high rate of resistant to
cephalexin 75 (53.6%), susceptible rate were 34 (24.3%)
and 31(22.1%) were intermediate.
The study showed that cephalexin had no activity
against Pseudomonas spp and was more effective
against Staph. aureus (100%) and Strepto. faecalis
(100%).
The rate of resistance among isolates recovered
from males was 59.6% and among isolates recovered
from females was 49.4%. Susceptibility rate to
cephalexin in females was 25.3% being higher than in
males 22.8%. Intermediate susceptibility rate in females
was 25.3% being higher than in males (17.5%)
