Frequency of ABO, Rhesus (D) and Duffy(Fya, Fyb) antigens, phenotypes in Bunni Aamer Sudanese tribe

Abstract

This descriptive, prospective and analytical study that aimed to determine the frequencies of Duffy antigens (Fya, Fyb), phenotypes, ABO blood group system phenotypes and Rhesus (D) factor. This study was conducted in Bunni Aamer tribe during the period of two months, following informed consent, a total of 100 venous blood samples were collected in 2.5 ml of blood EDTA container from unrelated individuals. The red cells were tested for Duffy antigens (Fya, Fyb) by using the particle gel immunodiffusion, for ABO blood group system and Rhesus (D) factor using slide method and Du method for the negative results. The study showed that the O phenotype was common with the frequency of (58 %); followed by B phenotype with frequency of (21 %), A phenotype with the frequency of (19 %) and AB phenotype with low frequency (2%).The Rhesus (D) was high frequent (97%). In Duffy blood group system the Fya antigen frequency was (14%), while the Fyb antigen with the frequency was (19 %) among the study group. The phenotype Fy (a-b-) frequency was (70 %), while the phenotype Fy (a-b+) frequency was (16 %), while the phenotype Fy (a+b-) was (11 %), and the phenotype Fy (a+b+) was (3%). The result of this study were compared with the results of other Sudanese ethnic groups it was found that there were similarity in some ABO blood group and Rh (D) factor with the Arrakein, Alshokria, Danagala and Shaigia and there were differences with the Halaween, Miseria and Nuba, while in the Duffy blood group system there was no previous study in other Sudanese ethnic groups. We conclude that the similarity between Sudanese tribes living in one area resulting from intermarriage between them, while that there were differences between the tribes living in different geographical area.