Abstract:
This is a case control descriptive analytical study conducted at
Khartoum city during the period from April to July 2013. The
aim of this study is to determine RBCs, Hb, Hct, MCV, MCH,
MCHC, TWBCs and platelets of Sudanese pregnant women with
diabetes
mellitus
attending
Alsaudi
Hospital,
Khartoum
Teaching Hospital, Khartoum North Teaching Hospital.
Fifty pregnant women with diabetes and twenty healthy
pregnant women were informed about the study and agreed
for participation.A Questionnaire was designed to collect
information about the study group such as age, gestational
age ,history of abortion and diabetes mellitus onset .
3ml of venous blood was collected in EDTA anticoagulant
container. Automated hematological analyser (sysmex Kx21N
was used to measure complete blood count .
The results indicated that RBCs of patients were insignificant
decreased compared to control in the three trimester.RBCs of
patients decrease insignificantly for the first trimester from
4.53±0.31x106/uLto
4.16±0.48x106/uL
in
the
third
trimester.Hb increase insignificantly from 11.7g/dLin control to
12.6±1.86 in patients in the second trimester,while Hb of
patients decrease significantly for the first trimester from
12.7±0.74g/dL to 11.7±1.39g/dLin
the third trimester( P.
value=0.04).No significant different in Hct of patients in the
three trimester.TWBCs of patients in three trimester showed
insignificant differences . platelets increased insignificantly at
second trimesters compared to those in first and third
trimesters.
RBCs of the patients in age group 30-40 years increased
significantly
from
3.78±0.25x106/
uL
in
control
to
4.30±0.38x106/uL No significant difference in Hb and MCV of
patients compared to control in all age groups .MCH and MCHC
in age group 30-40 years significantly decreased from 33.7 ±
2.22 pg to 2.29 ± 26.9pg and 36.1 ± 0.53g/dL to 32.8 ±1.67
g/dL respectively compared to control .Platelets significantly
different in patients in different age groups (.P.value=0.01) .
RBCs decrease insignificantly from 4.35±0.39x106/ uL in the
group with disease onset less than 6 years to 3.8x106/ uL in
the group of more than 13 years .while TWBCs decreased
insignificantly from 8.5±3.14x103/ uL in the first group to
5.2x103/ uL
in the group with disease onset more than 13
years. Platelets insignificantly increased in more than 13 years
onset of the disease.
Most of the hematological parameters of patients were
insignificantly differences in compared to control in different
trimester
.
No
significant
differences
in
hematological
parameters of patients in different trimester except Hb which
decrease significantly from first to the third trimester.
RBCs, Hb, Hct, MCV, MCH, MCHC, TWBCs and Platelets of
patients were insignificantly different in different duration of
diabetes mellitus.
