Abstract:
This study was carried out in Khartoum State from June to
December 2013. The aim of this study was to detect
herpes
simplex
virus
1and
2
in
Renal
Transplant
Recipients.
A total of 50 patients were included in this study. The
patients ages ranges from 18-65 years, and from both
gender. From the study participants, plasma samples were
collected, and tested for HSV1and2 IgM antibody using
Enzyme Linked Immune Sorbent Assay (ELISA) and for
HSV DNA by Polymerase Chain Reaction (PCR).
Out of the 50 patients, 1 (2%) was found to be positive by
ELISA, while, 11(22%) were positive by PCR. Out of 11
positive patient, 5 (45%) infected by HSV-1 and 6 (55%)
infected by HSV-2.
From the above finding we concluded that, there were a
high percentage of herpes simplex viruses in renal
transplant recipient in Sudan. PCR give more reliable
results in detection of HSV. We recommended the
screening of renal patients for HSV, and use of HSV DNA
as a diagnostic tool.
