Abstract:
Tuberculosis is a highly prevalent chronic infectious disease caused and it s still a
common disease in developed countries and still a major cause of mortality today, can
affect many part of the body like lungs and bones this defect can lead to defect most of
blood component (Sauders , 2007).
The aim of the study is to measure some hematological parameters among Sudanese
patients affected with pulmonary tuberculosis in Khartoum state. During the period
between April to August 2013 . 40 patients with pulmonary tuberculosis ( 25 males and
15 females) and 20 healthy controls (14 males and 6 females) were included . 2.5 ml of
blood was collected from patients and controls into EDTA containers then CBC Test
was carried out immediately after collection ,were carried out (Hb, RBCs count, HCT,
MCV, MCH, MCHC, TWBCs , platelet count and differential leukocyte count ) using
Hematological analyzer (Sysmex KX-21N). Data obtained was analyzed using software
program statistical package of social science (SPSS.V.11.5).
The results of pulmonary tuberculosis patients when compared with control showed that
there was significant lower values in Hemoglobin (Hb), Red Cell Count (RBCs) and
Packed Cell Volume (PCV) (P. 0.00) and within the normal range MCV(83.4±2 fl),
Mean MCH(30.1±4.3 pg) and MCHC (36.1±1.1 g/dl) in patients compared to controls
group . Total leukocyte count (TWBCs) and absolute Monocyte count was significantly
increase (P. 0.00) compared to controls group. The absolute Neutrophil count
significantly increase in patients (P. 0.008) compared to control group. Most common
type of anemia was normocytic normochromic anemia. Significantly increase in platelet
count was showed in patients (P. 0.00) compared to controls group.
Moderate normocytic normochromic anemia , leuckocytosis especially neutrophilia with
monocytosis and moderate thrombocytosis was observed in patients compared to controls
group. Absolute eosinophils and basophils count in patient was observed within normal
range compared to controls group.
