Susceptibility of Methicillin Resistant Staphylococcus Aureus to Selected Antibiotics

Abstract

This study had been conducted to determine the susceptibility of Methicillin-Resistant Staphylococcus aureus (MRSA) and staphylococcus aureus to selected antibiotics traditionally used in Sudan such as vancomycin, erythromycin, ciprofloxacin and gentamicin. Conventional techniques were used to isolate and identify S. aureus and MRSA strains. NCCLS modified-Kirby-Bauer disc diffusion technique had been used to carry out the susceptibility testing. A total of one hundred strains of S. aureus were isolated from the clinical specimens 36.6% from infected wound, 94.1% from ear infection and 59.1% from UTI patients. Only 21% of S. aureus isolates were MRSA. The resistance rate of oxacillin (represent methicillin), gentamicin, erythromycin and ciprofloxacin against S. aureus strains were 21%, 22%, 14% and 4% respectively. The resistance rate of oxacillin, gentamicin, erythromycin and ciprofloxacin against MRSA were 100%, 90.5%, 33.3% and 19.05 % respectively. All the MRSA strains were sensitive to vancomycin.