Abstract:
This research aimed to study the flavonoids of the heartwood of acacia
nilotica var adstringens, acacia nilotica var nilotica and leaves of
Lonchocarpus laxiflorus. From the methanolic extract, tow compounds (I
and II) were isolated from acacia nilotica var adstringens, two compounds
(III and IV) were isolated from acacia nilotica var nilotica and one
compound (V) was isolated from the leaves of Lonchocarpus laxiflorus.
These compounds were purified by different chromatographic techniques
and identified via spectroscopic tools: IR, UV,
1
HNMR and Mass
spectroscopy.
The isolated compounds were evaluated for their antimicrobial potential
against gram negative (Escherichia coli & Pseudomonasa eruginos) and
gram positive (Bacillus subtilis, Bacillus cereus & Staphylococcus aureus)
bacterial and fungal (Candida albicans). All compounds showed varying
biological activity except compound V.
