Evaluation of Serum Triglyceride, Cholesterol and High Density Lipoprotein Cholesterol levels among Sudanese Females with Polycystic Ovary Syndrome in Aljazeera State

Abstract

Poly Cystic Ovary Syndrome (PCOS) is a major health problem which affect women in reproductive age and lead to infertility and dyslipidemia. This study was carried out to measure serum level of High Density Lipoprotein cholesterol (HDL-c), Triglyceride (TG) and Total cholesterol in PCOS patients. Fifty samples were collected from PCOS patients in period between February to May 2020, chosen randomly from Elhasahesa Educational Hospital for gynecological and obstetrics in Aljazeera State, and Fifty apparently healthy individuals as control group. HDL.c and TG were measured by ROCHE DIAGNOSTIC – COBAS INTEGRA400 PLUS, and the results were analyzed using Statistical Package of Social Science (SPSS), computer program. The study showed that, serum level of TG and total serum cholesterol were increased and HDL.cwas decreased in PCOS patients compared to control group :TG(mean ± SD: 170 ± 8.5 mg/dl versus 87.3 ± 23.36 mg/dl, P.value (0.00),serumtotal cholesterol (mean ± SD: 213.44 ± 32.44 mg/dl versus 100.36 ± 27.7 mg/dl, P.value(0.00), HDL.-c(mean ± SD: 31.28 ± 4.2 mg/dl versus 66.7± 11.6 mg/dl, P.value(0.00). Also the finding of this study showed that, there were strong positive correlation TG, Total cholesterol and BMI(r-value 0.879, p-value 0.00, r- value 0.966, p-value 0.00)respectively, while there was negative correlation between HDL and BMI(r-value -0.863, p-value 0.00). There were no correlation between HDL.c, TG, total cholesterol and age of PCOS patients (r-value 0.073, p.value0.470) (r value -0.069, p.value 0.496, r-value -0.026, p-value 0.801) respectively. It is conclude that, the serum level of HDL.c decreased while serum level of total cholesterol and TGincreased among PCOS patients.