A study of the Flavonoids of Acacia tortilis and Acacia nubica and their Antimicrobial Activity

Abstract

In this study the flavonoids of two potentially beneficial medicinal plants- Acacia tortilis and Acacia nubica – have been studied. Phytochemical screening of Acacia tortilis stem bark revealed the presence of sterols and tannins. Acetyl-methyl flavonol and Acetyl-dimethyl dihydroflavonol have been isolated by paper chromatography from Acacia tortilis stem bark and their structures were partially elucidated via a combination of spectral techniques (UV, IR and 1HNMR). The ethanol extract of Acacia tortilis was screened for antimicrobial activity against five standard microorganisms. The extract showed partial anticandidal activity. From the stem bark of Acacia nubica two flavonoids compound Acetyl-trimethyl isoflavone and Acetyl trimehyl dihydroflavonol have been isolated and partially characterized using: (UV, IR 1HNMR). Acacia nubica ethanol extract exhibited significant antibacterial and antifungal activity against test organisms.