Evaluation of Platelet Count and Indices in Malaria Patients in Khartoum State

Abstract

Malaria remains one of the major health problem in the tropical and sub tropical countries particularly Africa and Asia, with increased morbidity and mortality rate. This study is conducted to analyze the effects of malaria on platelets count and indices. This is a case control study carried out in Khartoum State, to estimate platelets count and platelets indices in malaria patients in Khartoum State. Fifty patients and fifty healthy individual were enrolled in the study after taking their verbal consent. Venous blood (2.5ml) was collected from the participants in EDTA containers and gently mixed. Platelets count and Platelets indices were determined by automated Sysmex (KX-21) technique. The obtained data were analyzed by both Student's Independent T test using SPSS version 23.0 computer program. The platelet count C/cmm was decreased among case group 108.7± 22.2 and increased among control group 286.6 ± 32.4 (P.value =0.00), increase of mean MPV in the cases(10.9±0.90) compared with the control (9.4 ±0.85); (P.value =0.00), increase of mean PDW in the cases (13.4±1.9) compared with the control (11.2 ±1.5); (P.value=0.00). The Patients recorded significantly (P.value =0.00) higher values for P-LCR (29.1±8.6%) than the control (21.2%±6.0%). It is concluded that the platelets count and indices are affected in patients with Malaria.