Abstract:
Clinical Chemistry Laboratory are confronted with an ever-increasing workload with limited large-scale Medical Testing Laboratories, where turnaround-time (TAT) and lowest possible cost is a necessity to cater higher patient volume and wide range of Medical decision. Also, it allows enhanced repeatability or reproducibility, linearity, precision accurateness of patients results, in addition to over the course of twenty-four hours for a period of a week,the aim of the study was evaluate the analytical performance of A15 bio system automatic biochemistry.
data was analyzed by using the application of Excel.The evaluation of precisionwithin-laboratory Quality control materials of levels 1 and 2 were used for analyses. The repeatability and within-laboratory precision of the a-15 was evaluated using the 3 analytes. Quality control materials of each level were analysed twice on the same day (once in the morning and once in the afternoon) for 20 consecutive days. Evaluation of accuracy was done on 45 subjects with clinically significant values (distributed over the analytical measurement range) were used for analyses in accordance with the CLSI guideline EP05-A2.00 .The CVs of impressions for instrument using control material were below 1.19% ,0.60% ,1.40% respectively for urea, glucose and creatinine, with in run, between run and between day impression that for normal result ,and about high result of CVs which was 2.94% ,4.04% and 3.63% for urea within run ,between run and between day respectively ,1.5%,1,97% and 1.92% for glucose within run ,between run and between day impressions respectively. And about creatinine the CVs was 3.29% ,7.37% and 7.66% within run, between run and between day impressions respectively. The correlation coefficients for all 45 analytes were ＞0.975, suggesting that the two instruments produce comparably acceptable results.study conclude that evidenced good technical and analytical performance for A-15 clinical chemistry system. accuracy, precision, and correlation with our reference system demonstrated a good precision and reliability of Mindray, making this high throughput clinical chemistry system well suited for use in modern laboratories.
