Abstract:
Background: lipids are playing avital role in all aspects of life, and the ABO system is the most important system in a transfusion process.
The aim of this study was to associate between serum levels of total cholesterol, triglycerides, HDL-C, LDL-C and ABO blood group in healthy Sudanese individuals.
Materials and methods: This is a cross- sectional study conducted during the period from March 2019 to August 2020, the study includes 200 healthy individuals (50 of them were A blood group, 50 were O blood group, 50 were B blood group and 50 were AB blood group) in Khartoum state, to determine the ABO blood group type and serum cholesterol, triglyceride, HDL-C , LDL-C . The estimation of serum lipid profile was done by using Cobas 311 chemistry analyzer; Statistical analysis was done by using SPSS.
The Results: Showed that a significant increase in the means of serum cholesterol (with p value = 0.004) and triglycerides (P value = 0.000) between different blood groups with the highest mean of serum cholesterol (mean ± SD: 176.0 ± 42.5 mg/dl) and triglycerides (mean ± SD: 191.2 ± 130.6 mg/dl) in AB blood group. The study also find positive correlation between the serum cholesterol and age in blood group O, B, AB (R=0.399, P value=0.004), (R=0.431, P value=0.002), (R=0.403, P value=0.004) respectively. And also find positive correlation between the serum triglycerides and age in blood group A and O (R=0.463, P value=0.001), (R=0.408, P value=0.003) respectively. And positive correlation between LDL-C and age in blood group B and AB (R=0.385, P value=0.006), (R=0.463, P value =0.001) respectively.
Conclusion: Individuals with AB blood group found to have high levels of serum cholesterol and triglycerides when compared to other blood groups, and positive correlation between age and cholesterol , triglycerides and LDL-C in many blood groups.
