Abstract:
Helicobacter pylori (H.pylori) infection is responsible for several gastric disease especially major ulcers in the stomach and small intestine, acknowledged to contribute to the majority of gastric carcinoma cases worldwide. This study was conducted at Tasabih Medical Complex in Khartoum State Sudan during the period from March to October 2019, aimed to detect H.pylori among southern Sudan refugees. A total of 200 Patients of southern Sudan refugees, were involved in this study, Blood and stool sample were collected and tested by deferent methods using Immunochromatography test for the detection of (Antigen and Antibody), Enzyme Linked Immunosorbant Assay (ELISA) IgG and IgM and urea breath test (UBT). The data was analyzed by Statistical Package for Social Sciences (SPSS).
Out of 200 samples were collected from Southern Sudan refugees their age ranged from 1-80years old, with mean of (36.9 ±16.9 SD). Out of 200 sample 107(53.5%),123(61.5),102(51%), 116(58%) and105(52.2%) samples were found positive for Helicobacter pylori using UBT,ICT antigen, ICT antibody, ELISA IgG and ELISA IgM respectively. The present study revealed that there was no statistically significant association between the frequency of H. pylori infection and age and gender by using UBT (p value =0.4 and 0.13) respectively. Comparing the infection in newly coming refugees and old resident refugees, it was found that newly coming positively infected were 81/120(67.5%) while old were 26/80 (32.5%) by UBT (p value =0.00). It was found that refugees who are drink service water 41(80.5%) are more susceptible to infection by H.pylori than other sources by using UBT (p value =0.00). Compaired between three methods which found that UBT is more sensitive and specific than other methods.
