Characterization of Constituents ofDegenAlbasha(Albizialebbeck(L) Fixed Oil Seed using GC-MS and its Antimicrobial Activity

Abstract

Albizialebbeck(L) Benthisconsidered a repository of numerous types of bioactive compounds possessing varied therapeutic properties. The therapeutic potential of plants has been well explored over a very long time period. The present study was conducted to evaluate the phytochemical composition of the seeds extracts (Distilled Water and Petroleum ether) of Albizialebbeck (L) Benth. The phytochemical analysis showed that the aqueous extraction possess higher number of phytochemical constituents compared to other extract, Petroleum ether extract showed the absent of saponins and Tannis, compared to Aqueous extract absent only of terpens. The Albizialebbeck(L)Benth seedswas extracted by usingsoxhlet with solvent n- hexane gave amount of oil (3.5%v/w) and analyzed by GC-MS. The analysis revealed the presence of 16 components. The major components are: 9, 12-octadecadienoic acid (25.81%), 9-octadecenoic acid (15.27%),eicosanoic acid (27.80%) and Docosenoic acid (7.663%). In disc diffusion bioassay Albizialebbeck(L)Benth seedsoil showed activity against Escherichia coli (inhibition zone(15), Staphylococcus aureus(inhibition zone(15). It also exhibited significant partial activity against Bacillus subtilis(inhibition zone(12) Pseudomonas aeruginosa(inhibition zone(10)andCandidaalbicans(inhibition zone(10).