Hematological Changes in Stored Whole Blood in Central Blood Bank – Khartoum

Abstract

Blood transfusion is the process of referring blood or blood based product from one person into circulatory system of another to treat a certain medical condition. The blood bank is the section of the laboratory that processes and distributes blood products under the supervisions of medical director certified in transfusion medicine. This study was conducted to determine the effect of storage over varying periods on some hematological parameters. The study includes 100 blood samples donated to central blood bank in Khartoum State. All samples collected from donors who met the specifications required to donate blood. The Complete Blood Count (CBC) was performed on it immediately at the time of collection, and this was considered as control, then CBC performed at day 7, day 14, day 21 and day 28. The results of each week were compared with the control. Complete Blood Count (CBC) was measured by automated cell count (Sysmex KY21N) for each day of collection, changes of various hematological properties in stored blood was compared with control (Day 0). In the first (day 7) and second weeks (day 14) there were insignificant changes in all hematological parameters except for platelets, there was a significant decrease (mean of plt in first week =2.086 and p value =.005) compared to the control (mean of plt in control = 3.286), while in third (day 21) and fourth weeks (day 28) all changes that occurred with a significant decrease, except for the MCV, which was significantly increased (mean in day 28 =90.725, p value =.001 and mean of control 87.846) The study concluded that all hematological parameters that evaluated are affected by storage, but platelets are more affected which have a significant decrease in Day 7.