Evaluation of Glucose-6 Phosphate Dehydrogenase level and Complete Blood count among Sudanese Diabetes Mellitus Type2 Patients in Khartoum State

Abstract

This is Case Control study conducted between March and April, 2017 in Khartoum state among diabetic type 2 Sudanese patients who attended at the Almoalem Hospital to evaluate CBC and G6PD level.One hundred was confirmed diagnosis with Type 2 Diabetic Patients as Cases while the other hundred was healthy non Diabetic the controls. 5ml of anti coagulated venous blood was withdrawn from each participant for CBC analysis, G6PD activity testing and glucose test. Demographic characteristic of participants showed 61/200 of them were male (30.5%) and 139/200 were female (69.5%). Mean of age was 54 + 14 year. Age group 46-65 years 98/200 (49%) was the highest frequency, followed by 25-45 years 52/200 (26%) and 66-85 years 50/200 (25%), while duration of disease was the highest frequency 1-10 years 60/100 (60%), 11-20 years 29/100 (29%) and 21-30 years 11/100 (11%). Frequency regard to medication of cases, injection was 57/100 (57%) and tabs were 43/100 (43%). Comparison Means of G6PD level between Control and Case subjects showed no significant differences in means of G6PD activity (0.211). Comparison of Means of CBC parameters between Control and Case, showed significant difference in PCV ( 0.039), MCV (0.000) and MCH (0.02). Correlation between G6PD level and glucose level among study volunteers, showed no significant correlation (0.474), with intermediate negative Pearson Correlation (-0.51). Comparison means of G6PD level among cases according to therapy, showed no significant differences in means of G6PD (0.364). Comparison means of G6PD level among study volunteers according gender, showed no significant differences in means of G6PD (0.234). Comparison means of G6PD activity Between Groups according to age group among study volunteers, showed no significant differences in means of G6PD(0.998) .