Assessment of Serum Gonadotropin (LH and FSH) Levels among Sudanese Women with Polycystic Ovary Syndrome

Abstract

Background: Polycystic Ovarian Syndrome (PCOS) is one of the most common metabolic and reproductive disorders among women of reproductive age. The study was aimed to estimate Leutinizing hormone (LH) and Follicle Stimulating hormone (FSH) levels in women with PCOS. Method: A case control analytical study was conducted at Alsir Abu Hassan fertility center in Khartoum State, included 100 blood samples, 50 samples from women with PCOS and 50 from apparently health individual as controls, serum LH and FSH levels were measured by ELISA ( Enzyme linked immune sorbent assay) in case and control The data were analyzed using SPSS statistical analysis. Results: This study showed that the levels of LH was insignificantly increased with (p-value 0.149) and means ±SD 12.19± 20.60 while there was no change in level of FSH in polycystic ovary syndrome patients compared to control group. The study showed that there was no effect in LH level across menstrual regularity, duration, infertility, family history, cosmetics and use of medication with (p-value 0.149). infertility with (p-value 0.350), family history with (p-value 0.350), cosmetics with (p-value 0.378) and use of medication with (p-value 0.286). Also there was no change is FSH level. Conclusion: From the results and finding of this study, it is concluded that the Sudanese female with PCOs had normal levels of serum LH/ FSH hormone.