Sero- detection of IgG antibodies of Hepatitis C Virus in El-obeid City

Abstract

Hepatitis C is an infectious disease caused by Hepatitis C Virus (HCV). It is a major public health problem, and infection with this virus may lead to serious consequences such as liver cirrhosis and liver carcinoma. The objective of this study to detect IgG antibodies of Hepatitis C Virus in Elobeid City. The study was conducted during the period from March to October 2017. Ninety (90) subjects were enrolled in this study from both males and females, the age of the subjects range from (18-65) years old, participants were interviewed for risk factors using predesigned form. 5ML of blood were collected randomly from each subject. The blood was centrifuged at 2000 rpm for 5 minutes to obtain serum. The sera were tested by using fourth generation ELISA machine. Data was entered and analyzed with SPSS version 16 statistical software and was summarized and presented in tables. Reveal after risk factors including: (hemodialysis, history of jaundice, tattooing, surgery, multiple sex partners, intravenous drug and blood transfusion) the majority of subjects examined were males 67(73.4%) while females 23 (25.6%). All samples were tested give Negative result. According to the assay used this study indicates HCV is not prevalent in Elobeid City. Further studies with large sample size are needed to determine the rate of spreading of HCV among general population in Elobeid City and plans for prevent the spread of infection.