Assessment of Erythrocyte Sedimentation Rate, C - reactive protein and Red Cell Distribution Width among Myocardial Infarction Patients in Khartoum State

Abstract

Myocardial infarction (MI), commonly known as a heart attack, occurs when blood flow decrease or stop to part of the heart, causing damage to heart muscle. ESR and CRP are inflammatory biomarker which are elevated in inflammatory condition and also elevated in chronic diseases such as Cardiac diseases.RDW value increased indicate there are Anisocytosis in RBC and there is association between RDW and increase risk of cardiac diseases. This study is aimed to detect that there is relation between ESR, RDW, CRP levels and the morbidity and mortality in MI patients. This is analytical case control study conducted during the period of March 2019 to September 2019 in Khartoum state in Sudan Heart Center, A total of 70 subjects were included ,30 myocardial infract patients and 40 healthy individual from both sexes . A structured questionnaire was prepared which included general information and laboratory investigations; Verbal consent was obtained from each subject before evolvement in the study. The results showed Significant increased in mean level of ESR between case and control group (p .value = 0.00) , and there was significant increased in mean level of CRP between case and control group (p .value = 0.00) ,and there was significant increased in mean level of RDW between case and control group (p .value = 0.00) . Results showed that there was no significant increased in the mean of ESR in myocardial infract patients males compared to females ( p. value 0.2), and the mean of CRP between males and females (p. value 0.6).and the mean of RDW between males and females (p .value 0.9). According to age groups ( 20-50)and (51-80) there was no significant difference in the mean of ESR (p .value 0.3 ) , CRP (p .value 0.3 ) and RDW (p. value 0.1) in myocardial infarct patients.