Isolation and Characterization of Flavonoids From Weltheria indica , Cistanch phelypea and Fagonia critica and Their Biological Activity

Abstract

This study was carried out to investigate the flavonoids three key species in Sudanese traditional medicine: Wetheria indica , Cistanch phelypea and Fagonia critica. Three flavonoids ,one flavonoid from each plant, have been isolated and their tentative structures have been deduced on the basis of their spectral data. Furthermore the antimicrobial activity of these plants have been screened in vitro. The flavonoids were extracted with 95% ethanol and the crude extracts were purified by thin layer chromatography . The structures of the isolated flavonoids have been partially characterized by some spectral data (UV and 1HNMR). One flavonoid-compound I- was isolated from the leaves of Waltheria indica another one-compound II- was isolated from the leave of Cistanch phelypea , while a third flavonoid compound III- was isolated from Fagonia critica. ....................