Assessment of Serum Amino Transferases and Albumin among Hypertensive Patients in ELobied City -North Kordofan State

Abstract

Background: Hypertension is a long-term medical condition in which the blood pressure in the arteries is persistently elevated. Long-term high blood pressure, however, is a major risk factor for coronary artery disease, stroke, heart failure, atrial fibrillation, peripheral vascular disease, vision loss, chronic kidney disease, and dementia Objectives This study aims to estimate AST,ALT and albumin in patient with hypertension. Materials and methods: This study includes 100 participant, 50 of them have hypertension and the other are control group,5 ml of blood was taken from each participate to prepare serum, the serum prepared was used for the measurement of ALT,AST and albumin using BA400 (BIOCHEMISTRY ANALYZER) and the data obtained were analyzed using SPSS version 20. Results: This study included 50 female and male with hypertension and 50 without hypertension age matched, the mean concentration of AST,ALT, albumin were significantly increased among hypertensive patient(35.154±2.3184), (35.858±2.6679), (4.000±.3105) in comparison with control group (23.354±4.5197), (25.478±4.7412), (3.702±.1985) respectively with p value 0.000 , the mean concentration of AST,ALT was significantly increased among male group P value(0.002 )( 0.037) respectively in comparison with female group p value(0.002), ( 0.037)respectively. in contracts there is significant increase in mean concentration of albumin in female group in comparison with male group with (P value=0.034). Person’s correlation showed no correlation observed when associated serum AST, ALT, albumin with age of hypertension patient (r 0.013,p value 0.927)(r 0.078 p value 0.550)(r 0.107,p value 0.459) and there is no correlation observed when associate serum AST, ALT with duration of hypertension(r 0.204 p value 0.156)(r 0.239, p value 0.095) , and also serum Albumin not correlated with duration of hypertension patient(r 0.112 p value 0.440).