Comparative Study between Synovial Fluid and Serum Metabolites in Sudanese Cattle

Abstract

This study was conducted to establish Normal values for Total protein (TP),Albumin (Alb), Globulin (Gl), Glucose(G) and Alanine aminotransferase (ALT) from synovial fluids in Baggara Sudanese cattle , compared with the corresponding values in serum and to investigate the correlation and regression among serum and synovial fluid of these metabolites. Eleven blood samples and twenty two synovial fluid samples were collected from carpal and tarsal joints of clinically healthy Baggara bulls, during the period from January to March 2018. The colorometric methods were used to determine the concentration of these metabolites using commercial kits which were analysed using Spectrophotometer (UV mini-1240-Japan). The data was analysed by ANOVA and LSD using SPSS programme (version 16). The glucose concentration of carpal joint was significantly (p=0.024) lower than that of the tarsal joint and serum, while the other metabolites were significantly lower (p=0.000) than serum. The correlation (between total protein, albumin ,globulin, and ALT ,between albumin and globulin and between globulin and ALT ) and the subsequent simple linear equations of synovial fluid metabolites were established. In conclusion, data obtained will be useful as diagnostic tool to differentiate between normal and abnormal joints of cattle which will help in the diagnosis of joint disorders and diseases. The study recommends that, other studies of synovial fluid should be made in large number of cattle and comparison between synovial fluid metabolites and other body fluid metabolites such as cerebrospinal fluid should be done.