Serum Levels of Magnesium, and Creatinine in Sudanese Patients with Type 2 Diabetes Mellitus

Abstract

A cross-sectional study conducted during the period from December 2009 to August 2010, compared the serum levels of magnesium and creatinine of 50 Sudanese patients with type 2 diabetes mellitus (as a test group) and 30 apparently healthy volunteers (as a control group). Participants in this study were from Hajalsafi hospital and Khartoum north diabetic center, both in Khartoum state, Sudan. The serum levels of magnesium and creatinine were measured using reagent kits and a spectrophotometer (B.T.S-310) from Biosystem company. Serum magnesium was significantly reduced, whereas serum creatinine was significantly raised in the diabetic group when compared to the control group, (p<0.05). In the diabetic group, there was no correlation between the duration of the disease with both; the serum levels of magnesium and that of creatinine, whereas the body mass index of patients showed weak positive correlations with both; the serum levels of magnesium and that of creatinine. From this study, it is concluded that; in Sudanese patients with type 2 diabetes mellitus the serum levels of magnesium are reduced and the serum levels of creatinine are raised. The serum levels of magnesium and creatinine have weak positive correlations with the body mass index of the diabetic patients and no correlations with the duration of diabetes.