Assessment of Metastatic Behavior of Ovarian Carcinoma Using Bone Scintigraphy

Abstract

This study focused on the bone metastasis from ovarian cancer, therefore the main objective of this study was to evaluate the metastatic behavior of ovarian carcinoma using bone scan. This study was conducted at Radiation and Isotopes Center in Khartoum at the nuclear medicine department, in the period from March 2010 to Jun 2011. The data were collected from 50 patients with ovarian cancer. 99mTc-MDP was administered to the patients intravenously (20 mCi) and gamma camera ‘Philips’ was used. By using excel. The result showed the anatomical site of ovarian cancer metastasis in skeletal system, it reveals the predominant anatomical site being involved by ovarian cancer secondaries were the Pelvic bone, Thoracic vertebrae, ribs, skull, other organ (liver), which taking 18 %, 16 %, 12% ,12%, 12% respectively. While the spread to LV, CV, Diffused and coccyx are taking 10%, 10%, 8% and 2%. And the incidence of ovarian cancer was linearly associated with the age. The common encountered stage of ovarian cancer was stage IV representing 88% relative to other stages.