Oral Candidiasis in Sudanese Cancer Patients Receiving Different of Treatments for different cancer types

Abstract

This study was done to detect the prevalence of oral Candidiasis among Sudanese cancer patients with different cancer types who received different cancer treatment in Khartoum oncology hospital which formerly was known as Radio and Isotopes Centre of Khartoum (al Zarra Hospital) which recently named Khartoum Oncology Hospital. .A hundred oral swabs were collected from the patients with different age groups ranging from 2 to 83 old, 66\100 were males and 34\100 were females.The study was carried out in the period from May to July 2015. The study showed that the distribution of an oral Candidiasis among cancer patients was 40% and age group less than 20 years old were more affected with an oral Candidiasis. Study showed that males were most affected with an oral Candidiasis than females with 23%. All samples were first cultured on to Sabouraoud’s dextrose agar media which was supplemented with chloramphenicol antimicrobial agent, from those only 40% were showed growth. Then growth colonies identified by Gram's stain, methylene blue and sub cultured in serum for germ tube test and on chromogenic Candida agar media .There gave light green colonies were Candida albicans with (28%), which were the most prevalence strain of isolated Candida species, followed by Candida tropicalis which gave blue colonies with (8%) and then Candida kruzei with (4%) Candida tropicalis which gave creamy-moove colonies. Leukemic cancer patient were the most affected group among other patients diagnosed with different cancer types with (13%). The study showed that cancer patients that resident in Omdurman city and those from Gail tribe were the most affected with an oral candidiasis.