Browsing Volume 19 No. 1 by Subject "hepatocyte nuclear factor1α"

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Identification of (Ala98Val) and (Ile27Leu) Mutation in exon 1 of HNF1-α (MODY 3) And their Association with early-onset Diabetes in Sudanese Families

Osman, Abdelsadig Abdalazeem،; Nouraldayem Altayeb, Hisham; MohammedAbdel Hamid, Muzamil; Mohammed yousif, Galal (2018-06-01)

Maturity onset diabetes of the young (Mody3) is a monogenic form of diabetes. Gene defects in the Hepatocyte Nuclear Factor -1 alpha (HNF1-α) causes MODY3. HNF1-α gene located in the chromosome (12q24.2).A prevalent amino ...

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